Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025
See Kikawa et al (2025) for details on this study.
Briefly, this study used sequencing-based neutralization assays to measure titers to influenza viruses with HAs from seasonal H3N2 and H1N1 viruses representative of those circulating in the summer of 2025 against a set of human sera collected in late 2024 to spring of 2025.
The numerical data and computer code are at https://github.com/jbloomlab/flu-seqneut-2025
Titers for all sera
Interactive chart of titers
Per-serum neutralization titers
NIID
SCH
UWMC
EPIHK
FCI
Per-plate counts and curve fits
NIID
SCH
UWMC
EPIHK
FCI
Summary of data dropped during quality control
Notebook summarizing QC drops
Interactive charts summarizing human sera titers