Near real-time data on the human neutralizing antibody landscape to influenza virus as of the summer of 2026 to inform vaccine-strain selection
Study led by Caroline Kikawa, Andrew Butler, John Huddleston, and Jesse Bloom.
See the summary of key results for an overview of the results.
The numerical data and computer code are at https://github.com/jbloomlab/flu-seqneut-2026
Documentation of results rendered as of Thu Sep 10 16:42:39 2026
Titers for all sera
Per-serum neutralization titers
human
Per-plate counts and curve fits
human
Plate-to-plate correlations of titers (only for plates that share sera with other plates)
human
Summary of data dropped during quality control
Report summarizing QC drops
Library quality-control
Composition of the library pools
Balance of the library re-pools
Single virus per well infections
Interactive charts of human titers, tree colored by subclade
H1N1 recent strains
H3N2 recent strains
Interactive charts of human titers, vaccine strains
H1N1
H3N2
Interactive charts of titers before and after vaccination in the VIDRL cohorts
H1N1 recent strains
H1N1 vaccine strains
H3N2 recent strains
H3N2 vaccine strains
Interactive charts of human titers with sera split by relative titer
H3N2 recent strains, tree colored by subclade
H1N1 recent strains, tree colored by subclade
Protein structure visualizations
Reports