This plot correlates the mutation effects estimated in three other studies with the fitness effects estimated in the current study and full-spike deep mutational scanning from Dadonaite et al (2023) .
The mutation effects being used in the comparisons are from the following studies:
For Rodriguez-Rivas et al, only site estimates are provided so the correlation is with the site-mean estimated fitness and measured DMS values. For the other studies, the correlation is with the mutation effects. Each row only shows points for mutations/sites measured by all three methods.
See Bloom and Neher (2023) for a paper describing the work.
See https://github.com/jbloomlab/SARS2-mut-fitness for full computer code and data.
See https://jbloomlab.github.io/SARS2-mut-fitness/ for links to all interactive plots.
This plot is for the public_2024-11-06 dataset. Here are all plots for that dataset.