The top plot shows the correlation between log dN/dS estimates and the site-average mean estimated fitness effects of amino-acid mutations for each gene.
The bottom plot shows how well the site-average mutational effect measured in deep mutational scanning (DMS) experiments correlates with the site-average mean estimated fitness effects of mutations, or the log dN/dS values.
The plots are interactive and you can mouse over points for detail.
The dN/dS values are taken from here .
See Bloom and Neher (2023) for a paper describing the work.
See https://github.com/jbloomlab/SARS2-mut-fitness for full computer code and data.
See https://jbloomlab.github.io/SARS2-mut-fitness/ for links to all interactive plots.
This plot is for the gisaid_2024-04-24 dataset. Here are all plots for that dataset.