average correlation of fitness estimates for spike and non-spike proteins

Pearson correlation coefficients for fitness estimates for amino-acid mutations made from subsets of sequences from different clades or different geographic regions. Correlations are calculated separately for spike and non-spike mutations, and the x-axis indicates the threshold for minimum expected counts for a mutation to be included in the correlations. The correlations include only mutations at the sites with the same wildtype identity in the clades.

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See Bloom and Neher (2023) for a paper describing the work.

See https://github.com/jbloomlab/SARS2-mut-fitness for full computer code and data.

See https://jbloomlab.github.io/SARS2-mut-fitness/ for links to all interactive plots.

This plot is for the public_2023-10-01 dataset. Here are all plots for that dataset.