Pearson correlation coefficients for fitness estimates for amino-acid mutations made for sequences from different clades versus the protein divergence between clades. Correlations are calculated separately for spike and non-spike mutations. Use the radio button below the plot to choose the threshold for minimum expected counts for a mutation to be included in the correlations. The correlations include only mutations at the sites with the same wildtype identity in the clades. This plot only includes the clades with the largest numbers of sequences.
You can mouseover points for details.
See Bloom and Neher (2023) for a paper describing the work.
See https://github.com/jbloomlab/SARS2-mut-fitness for full computer code and data.
See https://jbloomlab.github.io/SARS2-mut-fitness/ for links to all interactive plots.
This plot is for the public_2024-04-19 dataset. Here are all plots for that dataset.