polyclonal package¶
polyclonal¶
Package for modeling mutational escape from polyclonal antibodies using deep mutational scanning experiments.
Importing this package imports the following objects into the package namespace:
It also imports the following alphabets:
Submodules¶
- alphabets
AAS
AAS_WITHGAP
AAS_WITHSTOP
AAS_WITHSTOP_WITHGAP
biochem_order_aas()
- pdb_utils
extract_atom_locations()
inter_residue_distances()
reassign_b_factor()
- plot
DEFAULT_NEGATIVE_COLOR
DEFAULT_POSITIVE_COLORS
TAB10_COLORS_NOGRAY
activity_wt_barplot()
color_gradient_hex()
corr_heatmap()
curves_plot()
lineplot_and_heatmap()
- polyclonal
Polyclonal
Polyclonal.epitopes
Polyclonal.mutations
Polyclonal.alphabet
Polyclonal.sites
Polyclonal.sequential_integer_sites
Polyclonal.wts
Polyclonal.epitope_colors
Polyclonal.data_to_fit
Polyclonal.spatial_distances
Polyclonal.mutations_times_seen
Polyclonal.distance_matrix
Polyclonal.DEFAULT_SCIPY_MINIMIZE_KWARGS
Polyclonal.activity_wt_barplot()
Polyclonal.activity_wt_df
Polyclonal.curve_specs_df
Polyclonal.curves_plot()
Polyclonal.epitope_harmonized_model()
Polyclonal.filter_variants_by_seen_muts()
Polyclonal.fit()
Polyclonal.hill_coefficient_df
Polyclonal.icXX()
Polyclonal.mut_escape_corr()
Polyclonal.mut_escape_df
Polyclonal.mut_escape_pdb_b_factor()
Polyclonal.mut_escape_plot()
Polyclonal.mut_escape_site_summary_df()
Polyclonal.mut_icXX_df()
Polyclonal.mut_icXX_plot()
Polyclonal.non_neutralized_frac_df
Polyclonal.prob_escape()
Polyclonal.site_level_model()
PolyclonalConcentrationError
PolyclonalFitError
PolyclonalHarmonizeError
- polyclonal_collection
PolyclonalAverage
PolyclonalBootstrap
PolyclonalCollection
PolyclonalCollection.models
PolyclonalCollection.model_descriptors
PolyclonalCollection.descriptor_names
PolyclonalCollection.unique_descriptor_names
PolyclonalCollection.epitopes
PolyclonalCollection.epitope_colors
PolyclonalCollection.alphabet
PolyclonalCollection.sequential_integer_sites
PolyclonalCollection.sites
PolyclonalCollection.default_avg_to_plot
PolyclonalCollection.activity_wt_barplot()
PolyclonalCollection.activity_wt_df
PolyclonalCollection.activity_wt_df_replicates
PolyclonalCollection.curve_specs_df
PolyclonalCollection.curve_specs_df_replicates
PolyclonalCollection.curves_plot()
PolyclonalCollection.hill_coefficient_df
PolyclonalCollection.hill_coefficient_df_replicates
PolyclonalCollection.icXX()
PolyclonalCollection.icXX_replicates()
PolyclonalCollection.mut_escape_corr()
PolyclonalCollection.mut_escape_corr_heatmap()
PolyclonalCollection.mut_escape_df
PolyclonalCollection.mut_escape_df_replicates
PolyclonalCollection.mut_escape_df_w_model_values
PolyclonalCollection.mut_escape_plot()
PolyclonalCollection.mut_escape_site_summary_df()
PolyclonalCollection.mut_escape_site_summary_df_replicates()
PolyclonalCollection.mut_icXX_df()
PolyclonalCollection.mut_icXX_df_replicates()
PolyclonalCollection.mut_icXX_df_w_model_values()
PolyclonalCollection.mut_icXX_plot()
PolyclonalCollection.non_neutralized_frac_df
PolyclonalCollection.non_neutralized_frac_df_replicates
PolyclonalCollection.prob_escape()
PolyclonalCollection.prob_escape_replicates()
PolyclonalCollectionFitError
create_bootstrap_sample()
fit_models()
- utils
MutationParser
shift_mut_site()
site_level_variants()
tidy_to_corr()