dms_variants documentation

dms_variants is a Python package written by the Bloom lab. It can be used to analyze deep mutational scanning of libraries of barcoded variants, and fit global epistasis models.

See below for information and examples of how to use this package.

Contents

• Installation
• Examples
  • Analyze simulated library of codon variants
  • Variants with deletion mutations
  • Libraries with secondary target genes
  • Compute probabilities of escape
  • Parse barcodes
  • Fitting gobal epistasis models with experimental “noise”
  • Formatting CodonVariantTable plots
• dms_variants package
  • dms_variants
  • Submodules
• package index
• Acknowledgements